GOD’S HEAVENLY CHALLENGE… ABSCESS
Etiology & Pathophysiology Abscesses are always accompanied with some level of pain. Apart from bacterial infection, swelling and inflammation are involved. Staphylococcus aureus bacteria, are gram-positive facultative aerobes, being the leading cause of abscesses. They can grow in the absence of oxygen and there are at least 36 species and 18 subspecies of the genus Staphylococcus. Staphylococcus aureus being the most prevalent one in human skin and soft tissue abscesses. Breaches of local defenses, like skin cuts or hair follicle disruptions, give easy access to staphylococcal invasion… with abscess formation as a result when the immune system is impaired. Subsequent pus production disseminate onto skin surfaces, as well as enter lymph and blood to manifest at new sites. S. aureus spread through the bloodstream and enter peripheral tissue, causing infectious lesions. Initially they induce inflammatory responses, which attract neutrophils, macrophages and other phagocytes. S. aureus replicate themselves while circulating in body fluids. Once having entered organ tissue, the bacteria attract immune cells and then replicate themselves to replace epithelia with lesions. S. aureus secretes coagulase (Coa) and activates prothrombin, with a resulting staphylocoagulase-prothrombin complex. This complex cleaves fibrinogen and fibrin peptides are formed, giving rise to clot formation. They are then able to form within a short period of time a staphylococcal abscess community (SAC) in the middle of the lesion. As the host immune cells arrive, the lesions grow, with destruction of healthy tissue, associated with neutrophil necrosis. The main defense against Staphylococcus aureus is by neutrophilic polymorphonuclear leukocytes, comprising mostly of white blood cells. Staphylococcal protein A (SpA) is released from the bacterial capsule in large amounts, which impedes phagocytosis by binding the Fcy component of the immunoglobulin molecule (antibody).
TARGETS Staphylococcus aureus PAIN INFLAMMATION
COUNTERACTIONS Anti-bacterial Analgesic and Anti-nociceptive Anti-inflammatory
1 Corinthians 10:13 “No trial has overtaken you that is not faced by others. And God is faithful: He will not let you be tried beyond what you are able to bear, but with the trial will also provide a way out so that you may be able to endure it. “ – NET Bible
GOD’S HEAVENLY GARDEN GRACE “WAY OUT”… Divine molecules locked up within his global garden…molecules such as…
DISCLAIMER This information published through “God’s Garden Gifts” website is provided for informational purposes only and any action on your part in response to the information provided on this website is at the reader's own discretion. “God’s Garden Gifts” makes no representations or warranties with respect to any information shared on this website regarding diagnosis, treatment, action, or application of any kind. Neither “God’s Garden Gifts”, nor any associated person, is liable for any direct or indirect claim, loss or damage resulting from use of this website.
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… and many, many, many more
GOD’S HEAVENLY CHALLENGE… ABSCESS
Etiology & Pathophysiology Abscesses are always accompanied with some level of pain. Apart from bacterial infection, swelling and inflammation are involved. Staphylococcus aureus bacteria, are gram- positive facultative aerobes, being the leading cause of abscesses. They can grow in the absence of oxygen and there are at least 36 species and 18 subspecies of the genus Staphylococcus. Staphylococcus aureus being the most prevalent one in human skin and soft tissue abscesses. Breaches of local defenses, like skin cuts or hair follicle disruptions, give easy access to staphylococcal invasion… with abscess formation as a result when the immune system is impaired. Subsequent pus production disseminate onto skin surfaces, as well as enter lymph and blood to manifest at new sites. S. aureus spread through the bloodstream and enter peripheral tissue, causing infectious lesions. Initially they induce inflammatory responses, which attract neutrophils, macrophages and other phagocytes. S. aureus replicate themselves while circulating in body fluids. Once having entered organ tissue, the bacteria attract immune cells and then replicate themselves to replace epithelia with lesions. S. aureus secretes coagulase (Coa) and activates prothrombin, with a resulting staphylocoagulase-prothrombin complex. This complex cleaves fibrinogen and fibrin peptides are formed, giving rise to clot formation. They are then able to form within a short period of time a staphylococcal abscess community (SAC) in the middle of the lesion. As the host immune cells arrive, the lesions grow, with destruction of healthy tissue, associated with neutrophil necrosis. The main defense against Staphylococcus aureus is by neutrophilic polymorphonuclear leukocytes, comprising mostly of white blood cells. Staphylococcal protein A (SpA) is released from the bacterial capsule in large amounts, which impedes phagocytosis by binding the Fcy component of the immunoglobulin molecule (antibody).
Back to Index Back to Index
TARGETS Staphylococcus aureus PAIN INFLAMMATION
COUNTERACTIONS Anti-bacterial Analgesic and Anti- nociceptive Anti-inflammatory
1 Corinthians 10:13 “No trial has overtaken you that is not faced by others. And God is faithful: He will not let you be tried beyond what you are able to bear, but with the trial will also provide a way out so that you may be able to endure it. “ – NET Bible
DISCLAIMER This information published through “God’s Garden Gifts” website is provided for informational purposes only and any action on your part in response to the information provided on this website is at the reader's own discretion. “God’s Garden Gifts” makes no representations or warranties with respect to any information shared on this website regarding diagnosis, treatment, action, or application of any kind. Neither “God’s Garden Gifts”, nor any associated person, is liable for any direct or indirect claim, loss or damage resulting from use of this website.
GOD’S HEAVENLY GARDEN GRACE “WAY OUT”… Divine molecules locked up within his global garden…molecules such as…
… and many, many, many more